The second reason this game is a premier matchup: two storied franchises who no longer rule their division, let alone their conference. For Pittsburgh, they have been up and down, where on any given Sunday, they can lose to the Tampa Bay Bucs or Cleveland Browns. Most times, they are being tested by some of the NFL's premier teams and that is when their best comes out.
So, against San Francisco, look for the Steelers to show that this season's opener against the New England Patriots is indicative of what you will see this season.
Even though the Steelers lost that game, they showed just how good a team has to be to best them.
Is San Francisco that good? This question leads into why this is the Game of the Week. Both these teams have a three-way battle ahead for supremacy within their division. Unlike the Steelers, the 49ers are considered a distant third, until they beat a formidable opponent.
Last Monday's win over the hapless Minnesota Vikings did not tell much, so look for the Niners to really try to open up the offense, which might lead to quite a few turnovers, playing right into Pittsburgh's hands.
The Over/Under should not be an issue, at roughly 31-20 for the Steelers.
This is a great test for both teams. Pick wisely, come back for Thursday's pick and Enjoy this playlist.