Here's a quick breakdown on how I see this unfolding:
Barty / Muguruza -->; winner plays Bencic in 4th Round
Shaparova / Kerber -->; winner plays Serena in 4th Round
Sloane / Konta --> winner plays Kvitova in 4th Round
Bertens / Mertens would likely meet in 4th Round
Karolina Pliskova has pretty much a cakewalk to the Semifinals
Simona Halep will face her first tough match in the 4th Round unless she stumbles to Azarenka.
Either player will face winner of matches between these players: Venus, Madison Keys, Sabalenka.
Osaka, seeded number two, is at the bottom of the draw where she has to deal with a bunch of young and/or mid-career players who show no fear:
Putintseva, Swiatek/Golubic; possibly Yastremska or Kenin.
If she gets through them, she will likely face Wozniacki in the 4th Round